The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CAPN2-20-RE | 20 (40 μL) | 200 μL |  |
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| CAPN2-20-OR | 20 (40 μL) | 200 μL |  |
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| CAPN2-20-GO | 20 (40 μL) | 200 μL |  |
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| CAPN2-20-GR | 20 (40 μL) | 200 μL |  |
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| CAPN2-20-AQ | 20 (40 μL) | 200 μL |  |
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The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Symbol : CAPN2
Gene Name : Calpain 2
Chromosome : CHR 1: 223,701,592-223,776,017
Locus : 1q41
Alt. Genes : TRIM28
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