The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CAMK2A-20-RE | 20 (40 μL) | 200 μL |  |
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| CAMK2A-20-OR | 20 (40 μL) | 200 μL |  |
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| CAMK2A-20-GO | 20 (40 μL) | 200 μL |  |
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| CAMK2A-20-GR | 20 (40 μL) | 200 μL |  |
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| CAMK2A-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
Gene Symbol : CAMK2A
Gene Name : Calcium/calmodulin dependent protein kinase II alpha
Chromosome : CHR 5: 150,289,839-150,219,490
Locus : 5q32
Alt. Genes : ZNF263
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