This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CALD1-20-RE | 20 (40 μL) | 200 μL |  |
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| CALD1-20-OR | 20 (40 μL) | 200 μL |  |
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| CALD1-20-GO | 20 (40 μL) | 200 μL |  |
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| CALD1-20-GR | 20 (40 μL) | 200 μL |  |
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| CALD1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : CALD1
Gene Name : Caldesmon 1
Chromosome : CHR 7: 134,779,412-134,970,728
Locus : 7q33
Alt. Genes : LRPPRC
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