This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BMX-20-RE | 20 (40 μL) | 200 μL |  |
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| BMX-20-OR | 20 (40 μL) | 200 μL |  |
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| BMX-20-GO | 20 (40 μL) | 200 μL |  |
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| BMX-20-GR | 20 (40 μL) | 200 μL |  |
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| BMX-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Symbol : BMX
Gene Name : BMX non-receptor tyrosine kinase
Chromosome : CHR X: 155,007,76-155,565,28
Locus : Xp22.2
Alt. Genes : ABI2
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