This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BMP7-20-RE | 20 (40 μL) | 200 μL |  |
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| BMP7-20-OR | 20 (40 μL) | 200 μL |  |
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| BMP7-20-GO | 20 (40 μL) | 200 μL |  |
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| BMP7-20-GR | 20 (40 μL) | 200 μL |  |
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| BMP7-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
Gene Symbol : BMP7
Gene Name : Bone morphogenetic protein 7
Chromosome : CHR 20: 572,666,50-571,687,52
Locus : 20q13.31
Alt. Genes : PLXNC1
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