BDKRB1 FISH Probe

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
BDKRB1-20-RE 20 (40 μL) 200 μL color Request Pricing
BDKRB1-20-OR 20 (40 μL) 200 μL color Request Pricing
BDKRB1-20-GO 20 (40 μL) 200 μL color Request Pricing
BDKRB1-20-GR 20 (40 μL) 200 μL color Request Pricing
BDKRB1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Gene Details

Gene Symbol : BDKRB1

Gene Name : Bradykinin receptor B1

Chromosome : CHR 14: 962,562,09-962,647,62

Locus : 14q32.2

Alt. Genes : CLEC3A

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