The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BAK1-20-RE | 20 (40 μL) | 200 μL |  |
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| BAK1-20-OR | 20 (40 μL) | 200 μL |  |
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| BAK1-20-GO | 20 (40 μL) | 200 μL |  |
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| BAK1-20-GR | 20 (40 μL) | 200 μL |  |
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| BAK1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Gene Symbol : BAK1
Gene Name : BCL2 antagonist/killer 1
Chromosome : CHR 6: 335,802,92-335,725,45
Locus : 6p21.31
Alt. Genes : PDZK1IP1
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