This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATP6V1H-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1H-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1H-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1H-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1H-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Symbol : ATP6V1H
Gene Name : ATPase H+ transporting V1 subunit H
Chromosome : CHR 8: 538,433,10-537,155,42
Locus : 8q11.23
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.