This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATP6V1B2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1B2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1B2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1B2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATP6V1B2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
Gene Symbol : ATP6V1B2
Gene Name : ATPase H+ transporting V1 subunit B2
Chromosome : CHR 8: 201,971,92-202,268,51
Locus : 8p21.3
Alt. Genes : AKAP9
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.