This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATP6AP1-20-RE | 20 (40 μL) | 200 μL |  |
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| ATP6AP1-20-OR | 20 (40 μL) | 200 μL |  |
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| ATP6AP1-20-GO | 20 (40 μL) | 200 μL |  |
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| ATP6AP1-20-GR | 20 (40 μL) | 200 μL |  |
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| ATP6AP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
Gene Symbol : ATP6AP1
Gene Name : ATPase H+ transporting accessory protein 1
Chromosome : CHR X: 154,428,631-154,436,516
Locus : Xq28
Alt. Genes : YAF2
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