ATP2A2 FISH Probe

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ATP2A2-20-RE 20 (40 μL) 200 μL color Request Pricing
ATP2A2-20-OR 20 (40 μL) 200 μL color Request Pricing
ATP2A2-20-GO 20 (40 μL) 200 μL color Request Pricing
ATP2A2-20-GR 20 (40 μL) 200 μL color Request Pricing
ATP2A2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]

Gene Details

Gene Symbol : ATP2A2

Gene Name : ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

Chromosome : CHR 12: 110,281,226-110,351,092

Locus : 12q24.11

Alt. Genes : LINC01587

Request Pricing

Lorem Ipsum is simply dummy text of the printing and typesetting industry.

Lorem Ipsum is simply dummy text of the printing and typesetting industry.