ATP1A2 FISH Probe

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ATP1A2-20-RE 20 (40 μL) 200 μL color Request Pricing
ATP1A2-20-OR 20 (40 μL) 200 μL color Request Pricing
ATP1A2-20-GO 20 (40 μL) 200 μL color Request Pricing
ATP1A2-20-GR 20 (40 μL) 200 μL color Request Pricing
ATP1A2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]

Gene Details

Gene Symbol : ATP1A2

Gene Name : ATPase Na+/K+ transporting subunit alpha 2

Chromosome : CHR 1: 160,115,729-160,143,590

Locus : 1q23.2

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