This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATOX1-20-RE | 20 (40 μL) | 200 μL |  |
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| ATOX1-20-OR | 20 (40 μL) | 200 μL |  |
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| ATOX1-20-GO | 20 (40 μL) | 200 μL |  |
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| ATOX1-20-GR | 20 (40 μL) | 200 μL |  |
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| ATOX1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
Gene Symbol : ATOX1
Gene Name : Antioxidant 1 copper chaperone
Chromosome : CHR 5: 151,758,648-151,742,821
Locus : 5q33.1
Alt. Genes : SERF2
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