This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATIC-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATIC-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATIC-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATIC-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ATIC-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
Gene Symbol : ATIC
Gene Name : 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Chromosome : CHR 2: 215,311,955-215,359,744
Locus : 2q35
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.