The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATG5-20-RE | 20 (40 μL) | 200 μL |  |
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| ATG5-20-OR | 20 (40 μL) | 200 μL |  |
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| ATG5-20-GO | 20 (40 μL) | 200 μL |  |
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| ATG5-20-GR | 20 (40 μL) | 200 μL |  |
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| ATG5-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Symbol : ATG5
Gene Name : Autophagy related 5
Chromosome : CHR 6: 106,325,819-106,184,475
Locus : 6q21
Alt. Genes : NUBP2
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