ATF4 FISH Probe

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ATF4-20-RE 20 (40 μL) 200 μL color Request Pricing
ATF4-20-OR 20 (40 μL) 200 μL color Request Pricing
ATF4-20-GO 20 (40 μL) 200 μL color Request Pricing
ATF4-20-GR 20 (40 μL) 200 μL color Request Pricing
ATF4-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]

Gene Details

Gene Symbol : ATF4

Gene Name : Activating transcription factor 4

Chromosome : CHR 22: 395,197,08-395,226,85

Locus : 22q13.1

Alt. Genes : ENAM

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