ASIC2 FISH Probe

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ASIC2-20-RE 20 (40 μL) 200 μL color Request Pricing
ASIC2-20-OR 20 (40 μL) 200 μL color Request Pricing
ASIC2-20-GO 20 (40 μL) 200 μL color Request Pricing
ASIC2-20-GR 20 (40 μL) 200 μL color Request Pricing
ASIC2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]

Gene Details

Gene Symbol : ASIC2

Gene Name : Acid sensing ion channel subunit 2

Chromosome : CHR 17: 341,568,05-330,130,86

Locus : 17q11.2-q12

Alt. Genes : PDZK1IP1

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