This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARID5B-20-RE | 20 (40 μL) | 200 μL |  |
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| ARID5B-20-OR | 20 (40 μL) | 200 μL |  |
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| ARID5B-20-GO | 20 (40 μL) | 200 μL |  |
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| ARID5B-20-GR | 20 (40 μL) | 200 μL |  |
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| ARID5B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Symbol : ARID5B
Gene Name : AT-rich interaction domain 5B
Chromosome : CHR 10: 619,012,53-620,969,47
Locus : 10q21.2
Alt. Genes : KIF20A
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