This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARID4B-20-RE | 20 (40 μL) | 200 μL |  |
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| ARID4B-20-OR | 20 (40 μL) | 200 μL |  |
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| ARID4B-20-GO | 20 (40 μL) | 200 μL |  |
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| ARID4B-20-GR | 20 (40 μL) | 200 μL |  |
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| ARID4B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : ARID4B
Gene Name : AT-rich interaction domain 4B
Chromosome : CHR 1: 235,328,239-235,166,894
Locus : 1q42.3
Alt. Genes : FEM1B
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