This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APOC1-20-RE | 20 (40 μL) | 200 μL |  |
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| APOC1-20-OR | 20 (40 μL) | 200 μL |  |
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| APOC1-20-GO | 20 (40 μL) | 200 μL |  |
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| APOC1-20-GR | 20 (40 μL) | 200 μL |  |
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| APOC1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Symbol : APOC1
Gene Name : Apolipoprotein C1
Chromosome : CHR 19: 449,142,46-449,193,48
Locus : 19q13.32
Alt. Genes : PSMD14
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