This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APH1B-20-RE | 20 (40 μL) | 200 μL |  |
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| APH1B-20-OR | 20 (40 μL) | 200 μL |  |
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| APH1B-20-GO | 20 (40 μL) | 200 μL |  |
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| APH1B-20-GR | 20 (40 μL) | 200 μL |  |
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| APH1B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
Gene Symbol : APH1B
Gene Name : Aph-1 homolog B, gamma-secretase subunit
Chromosome : CHR 15: 632,775,18-633,091,25
Locus : 15q22.2
Alt. Genes : RASA4
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