Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP1B1-20-RE | 20 (40 μL) | 200 μL |  |
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| AP1B1-20-OR | 20 (40 μL) | 200 μL |  |
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| AP1B1-20-GO | 20 (40 μL) | 200 μL |  |
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| AP1B1-20-GR | 20 (40 μL) | 200 μL |  |
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| AP1B1-20-AQ | 20 (40 μL) | 200 μL |  |
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Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Symbol : AP1B1
Gene Name : Adaptor related protein complex 1 beta 1 subunit
Chromosome : CHR 22: 293,885,82-293,276,79
Locus : 22q12.2
Alt. Genes : LRPPRC
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