The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANG-20-RE | 20 (40 μL) | 200 μL |  |
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| ANG-20-OR | 20 (40 μL) | 200 μL |  |
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| ANG-20-GO | 20 (40 μL) | 200 μL |  |
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| ANG-20-GR | 20 (40 μL) | 200 μL |  |
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| ANG-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2014]
Gene Symbol : ANG
Gene Name : Angiogenin
Chromosome : CHR 14: 206,841,76-206,941,85
Locus : 14q11.2
Alt. Genes : POP7
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