A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANAPC4-20-RE | 20 (40 μL) | 200 μL |  |
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| ANAPC4-20-OR | 20 (40 μL) | 200 μL |  |
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| ANAPC4-20-GO | 20 (40 μL) | 200 μL |  |
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| ANAPC4-20-GR | 20 (40 μL) | 200 μL |  |
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| ANAPC4-20-AQ | 20 (40 μL) | 200 μL |  |
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A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Gene Symbol : ANAPC4
Gene Name : Anaphase promoting complex subunit 4
Chromosome : CHR 4: 253,772,25-254,184,97
Locus : 4p15.2
Alt. Genes : HIPK3
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