ALOX5AP FISH Probe

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ALOX5AP-20-RE 20 (40 μL) 200 μL color Request Pricing
ALOX5AP-20-OR 20 (40 μL) 200 μL color Request Pricing
ALOX5AP-20-GO 20 (40 μL) 200 μL color Request Pricing
ALOX5AP-20-GR 20 (40 μL) 200 μL color Request Pricing
ALOX5AP-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

Gene Details

Gene Symbol : ALOX5AP

Gene Name : Arachidonate 5-lipoxygenase activating protein

Chromosome : CHR 13: 307,134,77-307,644,27

Locus : 13q12.3

Alt. Genes : FEM1B

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