This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALOX12-20-RE | 20 (40 μL) | 200 μL |  |
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| ALOX12-20-OR | 20 (40 μL) | 200 μL |  |
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| ALOX12-20-GO | 20 (40 μL) | 200 μL |  |
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| ALOX12-20-GR | 20 (40 μL) | 200 μL |  |
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| ALOX12-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
Gene Symbol : ALOX12
Gene Name : Arachidonate 12-lipoxygenase, 12S type
Chromosome : CHR 17: 699,379,0-701,073,5
Locus : 17p13.1
Alt. Genes : CD96
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