ALAD FISH Probe

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ALAD-20-RE 20 (40 μL) 200 μL color Request Pricing
ALAD-20-OR 20 (40 μL) 200 μL color Request Pricing
ALAD-20-GO 20 (40 μL) 200 μL color Request Pricing
ALAD-20-GR 20 (40 μL) 200 μL color Request Pricing
ALAD-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Gene Details

Gene Symbol : ALAD

Gene Name : Aminolevulinate dehydratase

Chromosome : CHR 9: 113,401,337-113,386,311

Locus : 9q32

Alt. Genes : FEM1B

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