This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKR1C1-20-RE | 20 (40 μL) | 200 μL |  |
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| AKR1C1-20-OR | 20 (40 μL) | 200 μL |  |
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| AKR1C1-20-GO | 20 (40 μL) | 200 μL |  |
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| AKR1C1-20-GR | 20 (40 μL) | 200 μL |  |
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| AKR1C1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
Gene Symbol : AKR1C1
Gene Name : Aldo-keto reductase family 1 member C1
Chromosome : CHR 10: 496,326,1-497,996,6
Locus : 10p15.1
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