This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AGR3-20-RE | 20 (40 μL) | 200 μL |  |
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| AGR3-20-OR | 20 (40 μL) | 200 μL |  |
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| AGR3-20-GO | 20 (40 μL) | 200 μL |  |
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| AGR3-20-GR | 20 (40 μL) | 200 μL |  |
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| AGR3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
Gene Symbol : AGR3
Gene Name : Anterior gradient 3, protein disulphide isomerase family member
Chromosome : CHR 7: 168,819,88-168,547,10
Locus : 7p21.1
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