This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AFDN-20-RE | 20 (40 μL) | 200 μL |  |
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| AFDN-20-OR | 20 (40 μL) | 200 μL |  |
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| AFDN-20-GO | 20 (40 μL) | 200 μL |  |
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| AFDN-20-GR | 20 (40 μL) | 200 μL |  |
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| AFDN-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]
Gene Symbol : AFDN
Gene Name : Afadin, adherens junction formation factor
Chromosome : CHR 6: 167,826,871-167,972,022
Locus : 6q27
Alt. Genes : ZNF263
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