Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADRA1A-20-RE | 20 (40 μL) | 200 μL |  |
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| ADRA1A-20-OR | 20 (40 μL) | 200 μL |  |
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| ADRA1A-20-GO | 20 (40 μL) | 200 μL |  |
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| ADRA1A-20-GR | 20 (40 μL) | 200 μL |  |
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| ADRA1A-20-AQ | 20 (40 μL) | 200 μL |  |
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Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
Gene Symbol : ADRA1A
Gene Name : Adrenoceptor alpha 1A
Chromosome : CHR 8: 268,709,93-267,381,12
Locus : 8p21.2
Alt. Genes : YAF2
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