| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TGIF1-DDX19B-20-RERE | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-REOR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-REGO | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-REGR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-REAQ | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-ORRE | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-OROR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-ORGO | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-ORGR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-ORAQ | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GORE | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GOOR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GOGO | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GOGR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GOAQ | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GRRE | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GROR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GRGO | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GRGR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-GRAQ | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-AQRE | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-AQOR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-AQGO | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-AQGR | 20 (40 μL) | 200 μL |
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| TGIF1-DDX19B-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]
Gene Symbol : TGIF1
Gene Name : TGFB induced factor homeobox 1
Chromosome : CHR 18: 341,192,6-345,841,1
Locus : 18p11.31
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : DDX19B
Gene Name : DEAD-box helicase 19B
Chromosome : CHR 16: 702,897,66-703,352,12
Locus : 16q22.1
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