This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MXD1BA-20-REGO | 20 (40 μL) | 200 μL |
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| MXD1BA-20-REGR | 20 (40 μL) | 200 μL |
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| MXD1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| MXD1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MXD1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MXD1BA-20-GROR | 20 (40 μL) | 200 μL |
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| MXD1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MXD1BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Gene Symbol : MXD1
Gene Name : MAX dimerization protein 1
Chromosome : CHR 2: 699,150,40-699,429,44
Locus : 2p13.3
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