This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MEF2DBA-20-REGO | 20 (40 μL) | 200 μL |
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| MEF2DBA-20-REGR | 20 (40 μL) | 200 μL |
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| MEF2DBA-20-ORGR | 20 (40 μL) | 200 μL |
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| MEF2DBA-20-GOGR | 20 (40 μL) | 200 μL |
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| MEF2DBA-20-GRRE | 20 (40 μL) | 200 μL |
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| MEF2DBA-20-GROR | 20 (40 μL) | 200 μL |
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| MEF2DBA-20-GRGO | 20 (40 μL) | 200 μL |
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| MEF2DBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Gene Symbol : MEF2D
Gene Name : Myocyte enhancer factor 2D
Chromosome : CHR 1: 156,500,841-156,463,720
Locus : 1q22
Alt. Genes : RBM12
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