Designing a FISH Probe has never been easier. With access to the entire RPCI library, you are able to select the BAC clone of your choice and label it with either a orange, green, red, gold, or aqua dye. Uncertain as to which clone to use? Our FISH probe design experts can assist you with selecting the right clone that covers your region of interest.
What is a custom FISH probe design?
Fluorescence in situ hybridization or FISH is a cytogenetic technique that combines BAC clones with a fluorescent dye which allows a researcher or a clinician to easily detect and localize the presence or absence of specific DNA sequences on chromosomes.What are custom FISH probe designs used for?
A bacterial artificial chromosome or BAC is a DNA construct, used in the production of FISH probes, that localizes to a specific part of the human or mouse genome. The Roswell Park BAC library consists of over 400,000 BAC clones which can be selected and labeled for your needs.FISH Probe Design Services
Our FISH technicians have spent the last 5 years perfecting the production of custom FISH probe designs. We select and grow BAC clones from the Roswell Park's RPCI library, the most comprehensive human genome library, and label them with the dye of your choice. All probes are validated using our proprietary backend sequencing software which confirms that the probe localizes to the expected location. The normal turnaround time for a custom FISH probe design is one week.Featured FISH Probe Panels
FGFR2 FISH Probe
A catalog probe designed using specific BAC clones that cover the FGFR2 gene allowing researchers and clinicians to detect mutations of the FGFR2 gene.
BRAF FISH Probe
This probe uses a combination of BAC clones covering the BRAF gene region and an orange florescent dye to detect BRAF gene mutations.
PIK3CA FISH Probe
The PIK3CA FISH probe localizes at the PIK3CA gene and emits a florescent single allowing researchers and clinicians to detect PIK3CA gene mutations.
ATM FISH Probe
Verify ATM gene deletions, duplications, translocations, and inversion using a FISH probe specifically designed to detect ATM gene mutations.
CCND1 FISH Probe
Identify and confirm a CCND1 gene deletion, duplication, translocation, or inversion using a standard CCND1 FISH probe.
EGFR FISH Probe
Verify EGFR gene deletions, duplications, translocations, and inversion using a FISH probe specifically designed to detect EGFR gene mutations.
