This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DAO-20-RE | 20 (40 μL) | 200 μL |  |
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| DAO-20-OR | 20 (40 μL) | 200 μL |  |
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| DAO-20-GO | 20 (40 μL) | 200 μL |  |
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| DAO-20-GR | 20 (40 μL) | 200 μL |  |
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| DAO-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]
Gene Symbol : DAO
Gene Name : D-amino acid oxidase
Chromosome : CHR 12: 108,880,072-108,901,042
Locus : 12q24.11
Alt. Genes : KIF20A
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