CRADD FISH Probe

This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
CRADD-20-RE 20 (40 μL) 200 μL color Request Pricing
CRADD-20-OR 20 (40 μL) 200 μL color Request Pricing
CRADD-20-GO 20 (40 μL) 200 μL color Request Pricing
CRADD-20-GR 20 (40 μL) 200 μL color Request Pricing
CRADD-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Gene Details

Gene Symbol : CRADD

Gene Name : CASP2 and RIPK1 domain containing adaptor with death domain

Chromosome : CHR 12: 936,773,41-938,948,39

Locus : 12q22

Alt. Genes : CLEC3A

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