| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABI1-CUBN-20-RERE | 20 (40 μL) | 200 μL |
|
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| ABI1-CUBN-20-REOR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-REGO | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-REGR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-REAQ | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-ORRE | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-OROR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-ORGO | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-ORGR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GORE | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GOOR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GOGO | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GOGR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GRRE | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GROR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GRGO | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GRGR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-AQRE | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-AQOR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-AQGO | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-AQGR | 20 (40 μL) | 200 μL |
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| ABI1-CUBN-20-AQAQ | 20 (40 μL) | 200 μL |
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Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008]
Gene Symbol : CUBN
Gene Name : Cubilin
Chromosome : CHR 10: 171,304,91-168,239,65
Locus : 10p13
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
Gene Symbol : ABI1
Gene Name : Abl interactor 1
Chromosome : CHR 10: 268,610,86-267,465,95
Locus : 10p12.1
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