ACACB Break Apart FISH Probe

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ACACBBA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
ACACBBA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
ACACBBA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
ACACBBA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
ACACBBA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
ACACBBA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
ACACBBA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
ACACBBA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : ACACB

Gene Name : Acetyl-CoA carboxylase beta

Chromosome : CHR 12: 109,112,665-109,268,225

Locus : 12q24.11

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